Coenzyme recognition and gene regulation by a flavin mononucleotide riboswitch

Flavin mononucleotide: the coenzyme of reduced diphosphopyridine nucleotide dehydrogenase.

From the particulate reduced nicotinamide adenine dinucleotide (DPNH) oxidase of beef heart, Mackler (3) has obtained a soluble DPNH dehydrogenase which was estimated to be approximately 90 to 95% homogenous when examined electrophoretically.l Similarly, when the enzyme was chromatographed on diethylaminoethyl cellulose with phosphate buffer, pH 7.5, in a gradient elution method (0.001 M to 0.0...

Flavin Mononucleotide: the Acid-extractable Flavin of the Dpnh-coenzyme Q Reductase of the Respiratory Chain.

Several D P N H dehydrogenases have been purified from heart mitochondria or heart-muscle preparationsl-L STRAUB'S enzym& has been shown by MASSEY 8 to be a form of lipoamide dehydrogenase (EC 1.6.4.3), while the relationship of the remaining preparations to the respiratory chain and to each other is obscure. The flavin extractable by acid t reatment has been reported to be FMN in some casesl, ...

Flavin mononucleotide enzyme electrode amplified by a bioelectrocatalytic cycle.

A highly specialized flavin mononucleotide riboswitch responds differently to similar ligands and confers roseoflavin resistance to Streptomyces davawensis

Streptomyces davawensis is the only organism known to synthesize the antibiotic roseoflavin, a riboflavin (vitamin B2) analog. Roseoflavin is converted to roseoflavin mononucleotide (RoFMN) and roseoflavin adenine dinucleotide in the cytoplasm of target cells. (Ribo-)Flavin mononucleotide (FMN) riboswitches are genetic elements, which in many bacteria control genes responsible for the biosynthe...

FQR1, a novel primary auxin-response gene, encodes a flavin mononucleotide-binding quinone reductase.

FQR1 is a novel primary auxin-response gene that codes for a flavin mononucleotide-binding flavodoxin-like quinone reductase. Accumulation of FQR1 mRNA begins within 10 min of indole-3-acetic acid application and reaches a maximum of approximately 10-fold induction 30 min after treatment. This increase in FQR1 mRNA abundance is not diminished by the protein synthesis inhibitor cycloheximide, de...